Newcastle United claimed their second Old Trafford victory over Manchester United since 1972 to avenge their Carabao Cup final defeat at Wembley and pile the pressure on home manager Erik ten Hag.
First-half goals from substitute Miguel Almiron and Lewis Hall, his first for the club, were followed up by a solo effort from Joe Willock on the hour to give Newcastle their biggest away win over their hosts in 93 years as they cruised into the quarter-finals.
It was another desperate day for Manchester United and Ten Hag, who have lost eight of their opening 15 games for the first time since the 1962-63 season.
Coming just three days after they suffered another three-goal home humiliation at the hands of Manchester City, the home side’s weaknesses were again cruelly exposed.
Newcastle win now meet Chelsea in the quarter finals.
Meanwhile Arsenal manager Mikel Arteta said “I’m disappointed with myself” after his side were knocked out of the Carabao Cup in the fourth round following a 3-1 defeat by West Ham.
Arteta made six changes to his starting XI, with Declan Rice, Bukayo Saka and captain Martin Odegaard on the bench.
The Arsenal side selected produced a below-par display – for which Arteta took the blame.
“I’m very disappointed. I’m responsible for that,” he said.
“We’re out of the Cup, we wanted to play a very different game and compete.
“The game took a direction because of the first goal but we have to see much more from the team and earn the right to win.